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1

An Alkanesulfonamide “Safety-Catch” Linker for Solid-Phase Synthesis

Backes, Bradley J., Ellman, Jonathan A.

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 120 KB

english, 1999

2

Treatment of Hydropsical Conditions Using Transcervical Gradual Fetal Fluid Drainage in Mares With or Without Concurrent Abdominal Wall Disease

Diel de Amorim, Mariana, Chenier, Tracey S., Card, Claire, Back, Bradley, McClure, J. Trenton, Hanna, Paul

Journal:

Journal of Equine Veterinary Science

Year:

2018

Language:

english

File:

PDF, 1.46 MB

english, 2018

3

A reverse-phase HPLC assay for measuring the interaction of polyene macrolide antifungal agents with sterols

Bradley J. Backes, Scott D. Rychnovsky

Journal:

Analytical Biochemistry

Year:

1992

Language:

english

File:

PDF, 449 KB

english, 1992

4

Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin

Backes, Bradley J., Harris, Jennifer L., Leonetti, Francesco, Craik, Charles S., Ellman, Jonathan A.

Journal:

Nature Biotechnology

Year:

2000

Language:

english

File:

PDF, 465 KB

english, 2000

5

Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation

Shin, Youngsook, Winans, Katharine A., Backes, Bradley J., Kent, Stephen B. H., Ellman, Jonathan A., Bertozzi, Carolyn R.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 204 KB

english, 1999

6

Comparison of Liquid Exfoliated Transition Metal Dichalcogenides Reveals MoSe2 to be the Most Effective Hydrogen Evolution Catalyst

Gholamvand, Zahra, McAteer, David, Backes, Claudia, McEvoy, Niall, Harvey, Andrew, Berner, Nina C, Hanlon, Damien, Bradley, Conor, Godwin, Ian, Rovetta, Aurlie, Lyons, Mike, Duesberg, Georg, Coleman,

Journal:

Year:

2016

Language:

english

File:

PDF, 1.47 MB

english, 2016

7

Atom-at-a-time laser resonance ionization spectroscopy of nobelium

Laatiaoui, Mustapha, Lauth, Werner, Backe, Hartmut, Block, Michael, Ackermann, Dieter, Cheal, Bradley, Chhetri, Premaditya, Düllmann, Christoph Emanuel, van Duppen, Piet, Even, Julia, Ferrer, Rafael,

Journal:

Year:

2016

Language:

english

File:

PDF, 1.39 MB

english, 2016

8

Impact of buffer gas quenching on the 1S0 → 1P1 ground-state atomic transition in nobelium

Chhetri, Premaditya, Ackermann, Dieter, Backe, Hartmut, Block, Michael, Cheal, Bradley, Düllmann, Christoph Emanuel, Even, Julia, Ferrer, Rafael, Giacoppo, Francesca, Götz, Stefan, Heßberger, Fritz Pe

Journal:

The European Physical Journal D / Atomic, Molecular, Optical and Plasma Physics

Year:

2017

Language:

english

File:

PDF, 621 KB

english, 2017

9

Prediction of sub-surface 37 Ar concentrations at locations in the Northwestern United States

Fritz, Bradley G., Aalseth, Craig E., Back, Henning O., Hayes, James C., Humble, Paul H., Ivanusa, Pavlo, Mace, Emily K.

Journal:

Journal of Environmental Radioactivity

Year:

2018

Language:

english

File:

PDF, 800 KB

english, 2018

10

Titelbild

Nicolas Winssinger, Jennifer L. Harris, Bradley J. Backes, Peter G. Schultz

Journal:

Angewandte Chemie

Year:

2001

File:

PDF, 142 KB

2001

11

Von Split-Pool-Molekülbibliotheken zu räumlich adressierbaren Mikro-Arrays und deren Einsatz in der funktionellen Proteomik

Nicolas Winssinger, Jennifer L. Harris, Bradley J. Backes, Peter G. Schultz

Journal:

Angewandte Chemie

Year:

2001

Language:

german

File:

PDF, 213 KB

german, 2001

12

Cover Picture

Nicolas Winssinger, Jennifer L. Harris, Bradley J. Backes, Peter G. Schultz

Journal:

Angewandte Chemie International Edition

Year:

2001

File:

PDF, 144 KB

2001

13

From Split-Pool Libraries to Spatially Addressable Microarrays and Its Application to Functional Proteomic Profiling

Nicolas Winssinger, Jennifer L. Harris, Bradley J. Backes, Peter G. Schultz

Journal:

Angewandte Chemie International Edition

Year:

2001

Language:

english

File:

PDF, 176 KB

english, 2001

14

ChemInform Abstract: Chiral N-Acyl-tert-butanesulfinamides: The “Safety-Catch” Principle Applied to Diastereoselective Enolate Alkylations.

Bradley J. Backes, Dean R. Dragoli, Jonathan A. Ellman

Journal:

Year:

1999

File:

PDF, 34 KB

1999

15

A strategy to profile prime and non-prime proteolytic substrate specificity

H. Michael Petrassi, Jennifer A. Williams, Jun Li, Christine Tumanut, Jared Ek, Takashi Nakai, Brian Masick, Bradley J. Backes, Jennifer L. Harris

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 642 KB

english, 2005

16

Parallel strategies for the preparation and selection of liver-targeted glucocorticoid receptor antagonists

Bradley J. Backes, Gregory L. Hamilton, Phong Nguyen, Denise Wilcox, Steven Fung, Jiahong Wang, Marlena Grynfarb, Annika Goos-Nilsson, Peer B. Jacobson, Thomas W. von Geldern

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 217 KB

english, 2007

17

Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit

Bradley J. Backes, Kenton Longenecker, Gregory L. Hamilton, Kent Stewart, Chunqiu Lai, Hana Kopecka, Thomas W. von Geldern, David J. Madar, Zhonghua Pei, Thomas H. Lubben, Bradley A. Zinker, Zhenping

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 409 KB

english, 2007

18

Activity Profile of Dust Mite Allergen Extract Using Substrate Libraries and Functional Proteomic Microarrays

Jennifer Harris, Daniel E. Mason, Jun Li, Keith W. Burdick, Bradley J. Backes, Teresa Chen, Aaron Shipway, Gino Van Heeke, Lucy Gough, Amir Ghaemmaghami, Farouk Shakib, François Debaene, Nicolas Winss

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 690 KB

english, 2004

19

Carbamates from alcohol diversity: a simple solution phase library method

Gregory L. Hamilton, Bradley J. Backes

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 78 KB

english, 2006

20

Dealkylative functionalization of tertiary amines with electron deficient heteroaryl chlorides

Gregory L. Hamilton, Bradley J. Backes

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 100 KB

english, 2006

21

Efficient preparation of S-aryl thioacetates from aryl halides and potassium thioacetate

Chunqiu Lai, Bradley J. Backes

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 144 KB

english, 2007

22

Solid support linker strategies

Bradley J Backes, Jonathan A Ellman

Journal:

Current Opinion in Chemical Biology

Year:

1997

Language:

english

File:

PDF, 754 KB

english, 1997

23

How primary care providers talk to patients about alcohol a qualitative study

Kinsey A. McCormick, Nancy E. Cochran, Anthony L. Back, Joseph O. Merrill, Emily C. Williams, Katharine A. Bradley

Journal:

Journal of General Internal Medicine

Year:

2006

Language:

english

File:

PDF, 770 KB

english, 2006

24

Synthesis of C-11 modified mifepristone analog libraries

Gregory L. Hamilton, Bradley J. Backes

Journal:

Molecular Diversity

Year:

2007

Language:

english

File:

PDF, 241 KB

english, 2007

25

Substrate specificity of the human proteasome

Jennifer L Harris, Phil B Alper, Jun Li, Martin Rechsteiner, Bradley J Backes

Journal:

Chemistry & Biology

Year:

2001

Language:

english

File:

PDF, 3.55 MB

english, 2001

26

How Primary Care Providers Talk to Patients About Alcohol: A Qualitative Study

Kinsey A. McCormick, Nancy E. Cochran, Anthony L. Back, Joseph O. Merrill, Emily C. Williams, Katharine A. Bradley

Journal:

Journal of General Internal Medicine

Year:

2006

Language:

english

File:

PDF, 129 KB

english, 2006

27

Chiral N-Acyl-tert-butanesulfinamides: The “Safety-Catch” Principle Applied to Diastereoselective Enolate Alkylations

Backes, Bradley J., Dragoli, Dean R., Ellman, Jonathan A.

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 223 KB

english, 1999

28

Biochemical characterization of prostasin, a channel activating protease

Aaron Shipway, Henry Danahay, Jennifer A. Williams, David C. Tully, Bradley J. Backes, Jennifer L. Harris

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 1018 KB

english, 2004

29

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

Dan Han, Alana G. Lerner, Lieselotte Vande Walle, John-Paul Upton, Weihong Xu, Andrew Hagen, Bradley J. Backes, Scott A. Oakes, Feroz R. Papa

Journal:

Year:

2009

Language:

english

File:

PDF, 2.11 MB

english, 2009

30

Catalytic Asymmetric Oxidation of tert -Butyl Disulfide. Synthesis of tert -Butanesulfinamides, tert -Butyl Sulfoxides, and tert -Butanesulfinimines

Cogan, Derek A., Liu, Guangcheng, Kim, Kyungjin, Backes, Bradley J., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 259 KB

english, 1998

31

Discovery and Structure−Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors

Pei, Zhonghua, Li, Xiaofeng, von Geldern, Thomas W., Longenecker, Kenton, Pireh, Daisy, Stewart, Kent D., Backes, Bradley J., Lai, Chunqiu, Lubben, Thomas H., Ballaron, Stephen J., Beno, David W. A.,

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 155 KB

english, 2007

32

Comparison of three radiotherapy modalities on biochemical control and overall survival for the treatment of prostate cancer: A systematic review

Bradley R. Pieters, Djuna Z. de Back, Caro C.E. Koning, Aeilko H. Zwinderman

Journal:

Radiotherapy and Oncology

Year:

2009

Language:

english

File:

PDF, 200 KB

english, 2009

33

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

Alana G. Lerner, John-Paul Upton, P.V.K. Praveen, Rajarshi Ghosh, Yoshimi Nakagawa, Aeid Igbaria, Sarah Shen, Vinh Nguyen, Bradley J. Backes, Myriam Heiman, Nathaniel Heintz, Paul Greengard, Simon Hui

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 1.88 MB

english, 2012

34

Carbon-Carbon Bond-Forming Methods on Solid Support. Utilization of Kenner's "Safety-Catch" Linker

Backes, Bradley J., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 271 KB

english, 1994

35

Activation Method to Prepare a Highly Reactive Acylsulfonamide “Safety-Catch” Linker for Solid-Phase Synthesis 1

Backes, Bradley J., Virgilio, Alex A., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 64 KB

english, 1996

36

Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

Wang, Likun, Perera, B Gayani K, Hari, Sanjay B, Bhhatarai, Barun, Backes, Bradley J, Seeliger, Markus A, Schürer, Stephan C, Oakes, Scott A, Papa, Feroz R, Maly, Dustin J

Journal:

Nature Chemical Biology

Year:

2012

Language:

english

File:

PDF, 7.63 MB

english, 2012

37

Discovery of ((4 R ,5 S )-5-Amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8 H )-yl)methanone (ABT-341), a Highly Potent, Selective, Orally Efficacious, and Safe Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Pei, Zhonghua, Li, Xiaofeng, von Geldern, Thomas W., Madar, David J., Longenecker, Kenton, Yong, Hong, Lubben, Thomas H., Stewart, Kent D., Zinker, Bradley A., Backes, Bradley J., Judd, Andrew S., Mul

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 190 KB

english, 2006

38

Expedient Solid-Phase Synthesis of Fluorogenic Protease Substrates Using the 7-Amino-4-carbamoylmethylcoumarin (ACC) Fluorophore

Maly, Dustin J., Leonetti, Francesco, Backes, Bradley J., Dauber, Deborah S., Harris, Jennifer L., Craik, Charles S., Ellman, Jonathan A.

Journal:

Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 79 KB

english, 2002

39

Impact of Hospice Disenrollment on Health Care Use and Medicare Expenditures for Patients With Cancer

Carlson, M. D. A., Herrin, J., Du, Q., Epstein, A. J., Barry, C. L., Morrison, R. S., Back, A. L., Bradley, E. H.

Journal:

Journal of Clinical Oncology

Year:

2010

Language:

english

File:

PDF, 103 KB

english, 2010

40

The Majorana Demonstrator radioassay program

Abgrall, N., Arnquist, I.J., Avignone, F.T., Back, H.O., Barabash, A.S., Bertrand, F.E., Boswell, M., Bradley, A.W., Brudanin, V., Busch, M., Buuck, M., Byram, D., Caldwell, A.S., Chan, Y.-D., Christo

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2016

Language:

english

File:

PDF, 1.04 MB

english, 2016

41

Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Kinase Ligands

Feldman, Hannah C., Tong, Michael, Wang, Likun, Meza-Acevedo, Rosa, Gobillot, Theodore, Lebedev, Ivan, Hari, Sanjay B, Gliedt, Micah J., Mitra, Arinjay K., Backes, Bradley J., Papa, Feroz R., Seeliger

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 1.95 MB

english, 2016

42

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] C18. EMERGING PATHWAYS AND SECONDARY HITS IN PULMONARY FIBROSIS - Inhibition Of IRE1± Activity Attenuates ER Stress-Induced Pulmonary Fibrosis

Ghosh, Rajarshi, Giacomini, Marilyn M., Backes, Bradley J., Sheppard, Dean, Oakes, Scott A., Papa, Feroz R.

Year:

2012

Language:

english

File:

PDF, 20 KB

english, 2012

43

[IEEE 2016 10th International Congress on Advanced Electromagnetic Materials in Microwaves and Optics (METAMATERIALS) - Creete, Greece (2016.9.19-2016.9.22)] 2016 10th International Congress on Advanced Electromagnetic Materials in Microwaves and Optics (METAMATERIALS) - Ag nanoparticle decorated graphene oxide: Fluorescence quenching and surface enhanced raman scattering

Gough, J. J., Siewerska, K. E., Mehigan, S., Hanlon, D., Backes, C., Gholamvand, Z., Szydloska, B. M., Blau, W. J., McCabe, E., Bradley, A. L.

Year:

2016

Language:

english

File:

PDF, 427 KB

english, 2016

44

Burnout and Self-Reported Patient Care in an Internal Medicine Residency Program

Shanafelt, T D, Bradley, K a, Wipf, J E, Back, a L

Journal:

Annals of Internal Medicine

Year:

2002

Language:

english

File:

PDF, 210 KB

english, 2002

45

Influence of Graphene Oxide/Ag Nanoparticle Composites on the Fluorescence Properties of Organic Dyes

Gough, John J, Siewerska, Katarzyna E, Mehigan, Sam, Hanlon, Damien, Backes, Claudia, Gholamvand, Zahra, Szydłowska, Beata M, Blau, Werner J, McCabe, Eithne, Bradley, A. Louise

Journal:

Journal of Nanoscience and Nanotechnology

Year:

2017

Language:

english

File:

PDF, 10.21 MB

english, 2017

46

A photoactivatable crosslinking system reveals protein interactions in the Toxoplasma gondii inner membrane complex

Choi, Charles Paul, Moon, Andy Seong, Back, Peter Sungmin, Jami‐Alahmadi, Yasaman, Vashisht, Ajay Amar, Wohlschlegel, James Akira, Bradley, Peter John, Coppens, Isabelle

Journal:

Year:

2019

Language:

english

File:

PDF, 10.71 MB

english, 2019

47

Development of a Chemical Toolset for Studying the Paralog-Specific Function of IRE1

Feldman, Hannah C., Vidadala, Venkata Narayana, Potter, Zachary E., Papa, Feroz R., Backes, Bradley J., Maly, Dustin J.

Journal:

ACS Chemical Biology

Year:

2019

Language:

english

File:

PDF, 5.52 MB

english, 2019

48

A photoactivatable crosslinking system reveals protein interactions in the Toxoplasma gondii inner membrane complex

Choi, Charles Paul, Moon, Andy Seong, Back, Peter Sungmin, Jami‐Alahmadi, Yasaman, Vashisht, Ajay Amar, Wohlschlegel, James Akira, Bradley, Peter John, Coppens, Isabelle

Journal:

Year:

2019

File:

PDF, 10.71 MB

2019

49

Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required for Toxoplasma apical complex biogenesis

Back, Peter S., OâShaughnessy, William J., Moon, Andy S., Dewangan, Pravin S., Hu, Xiaoyu, Sha, Jihui, Wohlschlegel, James A., Bradley, Peter J., Reese, Michael L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 1.69 MB

2020

50

Targeting Adaptive IRE1Î± Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib

Yamashita, Yusuke, Morita, Shuhei, Hosoi, Hiroki, Kobata, Hiroshi, Kishimoto, Shohei, Ishibashi, Tatsuya, Mishima, Hiroyuki, Kinoshita, Akira, Backes, Bradley J., Yoshiura, Koh-Ichiro, Papa, Feroz R.,

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 2.04 MB

2020